The use of biodegradable polymers in medicine and biomedical research is increasing. A key growth area has been the use of these materials in tissue engineering, especially for guided regeneration of bone and cartilage. Our interest has been in determining the mechanisms by which cellular attachment and growth occurs on these materials. In the current study, we examined human osteoblast cell ad...

Nifedipine is a hypertension drug must be consumed three times a day due to its low oral bioavailability. One way of developing a controlled drug delivery system is making nifedipine microcapsules by using environmentally friendly polymers of polylactic acid and polycaprolactone via the evaporation method using oil-in-water solvents. Polylactic acid and polycaprolactone can be said to be enviro...

objective(s): the current study reports the production and biocompatibility evaluation of a ternary nanocomposite consisting of ha, pla, and gelatin for biomedical application.materials and methods: hydroxyapatite nanopowder (ha: ca10(po4)6(oh)2) was produced by burning the bovine cortical bone within the temperature range of 350-450 oc followed by heating in an oven at 800. synthesis of the te...

conclusions after paravertebral implantation of rifapentine polylactic acid sustained-release microspheres, the concentration of rifapentine in local vertebral bone tissues was maintained above the tb minimum inhibitory concentration for up to 60 days with no apparent accumulation of the drug in other tissues. methods this study is a basic animal experimental study that began on july 17, 2014 i...

This website provides an excellent overview of PLA as a polymer, its properties, and manufacture. This web article describes the production of lactic acid from biomass by microbial fermentation coupled to a poly-merization process to make PLA. The article is a bit dated and its industrial projections are now seen to be a bit over-optimistic. NatureWorks is the company that started large-scale p...

Polylactic acid was combined with lemongrass essential oil (EO) to produce functional nanocapsules (NCs). The obtained polylactic acid nanoparticles showed antimicrobial activity both with and without the presence of lemongrass oil; however, the presence of EO improved the activity of the NCs. The presence of lemongrass assisted the formation of well-separated NCs and also provided enhanced ant...

Alkylmethoxypyrazines (MPs) are a class of compounds that can elicit undesirable aroma and flavor characteristics in wine, and resist remediation using traditional wine making approaches. MPs are grape-derived constituents as well as contaminants from Coccinellidae beetles present during wine processing; the latter eliciting an off-flavor referred to as 'ladybug taint'. In this study we investi...

Today, the economic consumption of biodegradable polymers is of capital importance in many applications. One of the most commonly used biopolymers is polylactic acid (PLA). The printability of the biodegradable film has not been fully investigated. This work tested the printability of polylactic acid (PLA) films and compared the print qualities to common packaging films like low density pol...